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Algal Omics - A Systems Biology Approach to Microalgal Research and Applications
Parminder Kaur Narang, L Madhu Yashpal, and L Soma Ghorai
Abstract:
Microalgae are used extensively today to produce carotenoids for
commercial purposes and serve as an excellent model for research on
the metabolism of the carotenogenesis pathway in plants. Recently,
with the emergence of high-throughput omics technologies, such
as genomics, transcriptomics, and metabolomics, information
about microalgal metabolism has led to the use of microorganisms
from diverse lineages in producing bio-based feedstock and
many bioactive compounds. The evolution of omics technologies
has enabled systems biology to develop a comprehensive global
metabolic network, allowing researchers to generate and
analyze vast amounts of data on microalgal metabolism. It has
signifi cantly enhanced our understanding of cellular physiology and
regulatory mechanisms. However, microalgal strain improvement
necessitates appropriate engineering methods that enable the
complete biotechnological potential of microalgae to be realized.
This review paper describes the crucial role of algomics studies
in enhancing microalgal production and its various byproducts,
thereby facilitating the commercial production of these organisms.
Keywords: Microalgae, Carotenoid accumulation, Carotenogenesis,
Functional annotation, Algal omics, Genomics, Proteomics
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